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Association of body mass index with kidney function and mortality in high cardiovascular risk population: A nationwide prospective cohort study

Nephrology Sep 04, 2021

Aiumtrakul N, Kittithaworn A, Supasyndh O, et al. - A body mass index (BMI) of 35 kg/m 2 or more is correlated with loss of kidney function and mortality in the high cardiovascular (CV) risk Thai population. A BMI of less than 20 kg/m 2 is, on the other hand, associated with all-cause mortality.

  • The sample consisted of 5,887 candidates (3,217 male and 2,670 female) with high CV risk.

  • Participants' baseline BMI was used to divide them into five groups; < 20 kg/m 2 (n = 482), 20-24.9 kg/m 2 (n = 2,437), 25-29.9 kg/m 2 (n = 2,140), 30-34.9 kg/m 2 (n = 665), and 35 kg/m 2 (n = 163), respectively.

  • Baseline BMI ≥ 35 kg/m 2 was an independent predictor of loss of kidney function and all-cause mortality in a multivariate analysis of Cox proportional hazards models adjusted for other covariates.

  • A baseline BMI <20 kg/m 2 was also an independent predictor of all-cause mortality.

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