González-Callejas C, Aparicio VA, De Teresa C, et al. - Researchers sought to ascertain if and how body mass index (BMI) and some serum tissue damage markers are associated with postoperative pain. In addition, they determined biochemical marker cutoff point that may aid in predicting moderate to severe postoperative pain. They conducted cross-sectional study of 96 adult male patients (55 ± 13 years old) who underwent an inguinal hernioplasty. A visual analog scale (VAS) was used to determine postoperative pain (eight hours after surgery). In contrast to assumptions, findings suggested no correlation of greater BMI with higher postoperative pain. Greater postoperative pain was observed to be correlated with serum fibrinogen level, serum LDH concentration and alcohol consumption. They suggest assessment of serum LDH as valuable for attaining information concerning prediction of moderate to severe postoperative pain. An LDH concentration > 204 IU/L was noted to be linked with a three-times elevated odds ratio of moderate to severe postoperative pain.