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Association of arsenic exposure with cardiac geometry and left ventricular function in young adults: Evidence from the Strong Heart Family Study

Circulation: Cardiovascular Imaging May 10, 2019

Pichler G, et al. - Among 1,337 young adult participants from the SHFS (Strong Heart Family Study), researchers focused on the cross-sectional and prospective link between arsenic exposure and echocardiographic measures of left ventricular (LV) geometry and functioning. The participants were free of diabetes mellitus and cardiovascular disease. An association of arsenic exposure with an increase in LV wall thickness and LV hypertrophy was evident in these patients. Those with prehypertension or hypertension demonstrated a stronger association, which implies that those already undergoing cardiovascular adaptive mechanisms after raised systemic blood pressure might suffer more pronounced potential cardiotoxic impacts of arsenic.

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