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Association between serum activin A and metabolic syndrome in older adults: Potential of activin A as a biomarker of cardiometabolic disease

Experimental Gerontology Aug 09, 2018

Peng LN, et al. - Researchers investigated the potential of serum activin A (a member of the transforming growth factor-β superfamily) as a biomarker of cardiometabolic risk in 433 community-dwelling adults age ≥ 53 years from Yilan County, Taiwan. They analyzed data from these subjects and found significant correlation of high activin A with age, relative appendicular skeletal muscle mass in both genders, waist circumference in women, current alcohol drinking, hypertension, and Charlson Comorbidity Index. They observed a dose-dependent relationship between serum activin A levels, age, and metabolic syndrome, which infers that activin A may be a biomarker of overall cardiometabolic risk.

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