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Association between plasma free fatty acid levels and primary angle‐closure glaucoma based on a mass spectrometry metabolomics analysis

Acta Ophthalmologica May 06, 2021

Qin Y, Feng X, Luo H, et al. - Researchers intended to determine if there is an association between plasma free fatty acid (FFA) levels and primary angle‐closure glaucoma (PACG). The levels of FFA in PACG patients (n = 181) and people without glaucoma (n = 340) were compared. Using metabolomics analysis, 22 FFAs and six lipid classes were measured. Most FFAs were lower in the PACG group than those in the non‐glaucoma group. Lipid peroxidation can be linked to a decrease in FFA levels. Total saturated fatty acids and docosahexaenoic acid can be used as screening indices for PACG patients.

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