Association between physical activity and risk of depression
JAMA Psychiatry Jun 04, 2022
Why this study matters
Physical activity, even at one-half the public health recommended amount, will reduce the risk of depression, thus preventing up to 1 in 9 cases of depression.
PubMed, SCOPUS, Web of Science, PsycINFO, and the reference lists of systematic reviews were searched for prospective studies involving physical activity and risk estimates for depression.
Results and conclusion
This review included 15 studies, 190,131 participants, and 2,110,588 person-years of relevant data.
An inverse curvilinear association was demonstrated between physical activity and risk of depression. Participants who engaged in minimal exercise were at the greatest risk for depression. Specifically, adults who achieved the full and one-half of the recommended marginal metabolic equivalent task (mMET) hours each week, had a 25% and 18% lower risk of depression, respectively.
It was estimated that if all of the participants met the recommended mMET hours each week, 11.5% of depression cases would have been averted.
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