Liu T, Han C, Sun L, et al. - Among inpatients (n = 259) with a suspicion of having acute coronary syndrome who underwent coronary angiography, researchers assessed the diagnostic as well as the risk predictive value of emerging proinflammatory and anti-inflammatory adipocytokines on coronary artery disease (CAD). By means of ELISA, levels of serum inflammatory adipocytokines were assessed. They assigned inpatients to the CAD (n = 180) and control groups (n = 79). Significantly higher serum levels of retinol-binding protein-4 (RBP4), pentraxin 3 (PTX3), galectin-3 (GAL-3), and plasminogen activator inhibitor (PAI-1), and significantly lower levels of netrin-1 (NTN1), interleukin-37 (IL-37), and adiponectin (ADP) were observed in the CAD group vs in the control group. In the three-vessels CAD subgroup, they noted significant upregulation of PAI-1 and significant downregulation of IL-37 and ADP than the one- and two-vessels CAD subgroups. As far as the diagnosis and risk evaluation of CAD patients was concerned, findings revealed the superior effectiveness of inflammatory adipocytokines GAL-3, RBP4, PTX3, NTN1, and IL-37 than the classical biomarkers PAI-1 and ADP.