Vallée A, et al. - Researchers undertook this cross-sectional analysis to determine the links between lipid parameters and aortic stiffness. This inquiry was run from 2012 to 2017 and involved 603 participants, including 517 patients and 86 ‘healthy’ people, in whom the theoretical pulse wave velocity (PWV) was computed. Aortic stiffness was defined as a PWV index [(measured PWV − theoretical PWV)/theoretical PWV] greater than 0. A significant correlation with PWV was demonstrated by total cholesterol, LDL, non-HDL, total cholesterol/HDL and LDL/HDL in multiple linear regression analyses. Overall, findings revealed a significant link of non-HDL, total cholesterol, and total cholesterol/HDL, with aortic stiffness, compared with others and particularly individually lipid parameters. Considering this finding in future clinical lipid-lowering trials was recommended.