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Association between added sugar intake and mortality is nonlinear and dependent on sugar source in 2 Swedish population–based prospective cohorts

American Journal of Clinical Nutrition Feb 13, 2019

Ramne S, et al. - In two prospective population-based cohorts, researchers assessed the links between added and free sugar intake, intake of different sugar sources, and mortality risk. They obtained dietary data from the Malmö Diet and Cancer Study (MDCS; n = 24,272) as well as from the Northern Swedish Health and Disease Study (NSHDS; n = 24,475). They used a multivariable Cox proportional hazards regression to assess the links between the measured sugar intakes and mortality. In general, findings revealed higher sugar consumption was related to a less favorable lifestyle. With added sugar intakes between 7.5% and 10% of energy (E%) intake, the lowest mortality risk was reported in both cohorts. A 30% increased mortality risk was observed in relation to intakes >20E%, but intakes <5E% were also associated with increased risks. They found a positive association of sugar-sweetened beverage intake with mortality; the intake of treats was inversely associated. Overall, an increased mortality risk was observed in relation to a high sugar intake. Despite a more favorable lifestyle in general, low sugar consumers also had increased risk. The links were dependent on the type of sugar source.

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