Fernandez-Botran R, Furmanek S, Ambadapoodi RS, et al. - Researchers examined how the levels of biomarkers at hospital admission are linked with the risk of severe outcomes, including admission to the ICU, need for invasive mechanical ventilation (IMV), need for vasopressor use (VU), and in-hospital mortality (IHM) in 700 patients hospitalized with COVID-19.

• Analysis revealed the following as risk factors for ICU admission: hyper-inflammation and reduced respiratory function (RF).

• Low platelets, abnormal neutrophil-lymphocyte ratio, and reduced RF were identified to be linked with the risk for IMV.

• Hyperinflammation, low platelets and reduced RF were the risk factors for VU.

• For hospital mortality, risk factors included hypercoagulability and reduced RF and kidney function.