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Association among dietary supplement use, nutrient intake, and mortality among U.S. adults: A cohort study

Annals of Internal Medicine May 07, 2019

Chen F, et al. - In this study, researchers examined the link between dietary supplement use, food and supplement nutrient intake levels, and mortality among adults in the United States. Study participants included 30,899 adults (aged ≥ 20 years) who responded to questions on dietary supplement use from the National Health and Nutrition Examination Survey. In all, 3,613 deaths occurred during a median follow-up of 6.1 years, including 945 deaths from cardiovascular disease (CVD) and 805 deaths from cancer. The investigators noted an association of adequate intake of vitamins A and K, magnesium, zinc, and copper with decreased all-cause or CVD mortality, but associations were limited to food intake of nutrients. Overall, the authors concluded that the use of dietary supplements is not linked to US adult mortality benefits.

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