Gorka K, Gross-Sondej I, Górka J, et al. - This research sought to explore the structural changes of the airways using the endobronchial ultrasound (EBUS) in asthma-chronic obstructive pulmonary disease overlap (ACO) patients compared to severe asthma and chronic obstructive pulmonary disease (COPD) patients. Researchers enrolled 17 patients with ACO, 17 patients with COPD and 33 patients with severe asthma. They obtained detailed clinical data from all participants. They conducted basic laboratory tests, including measurement of eosinophil counts in blood and serum immunoglobulin E (IgE) concentrations. The outcomes demonstrate that the process of structural changes in the airways evaluated by EBUS is more advanced in individuals with ACO compared to patients with COPD, and less pronounced compared to patients with severe asthma. It appears that EBUS may provide beneficial information about differences in airway remodeling between ACO, COPD and severe asthma.