• Profile

Aortic pulse wave velocity as adjunct risk marker for assessing cardiovascular disease risk: Prospective study

Hypertension Feb 12, 2022

In a cohort of elderly people, aortic stiffness predicted major adverse cardiovascular events, enhancing the performance of a broadly employed cardiovascular disease risk estimator. Aortic pulse wave velocity measurement is scalable, radiation-free, and easy to perform.

  • If aortic pulse wave velocity identifies people with higher risk of incident major adverse cardiovascular events and improved performance of the American Heart Association/American College of Cardiology atherosclerotic cardiovascular disease risk score was investigated.

  • In this prospective study, a total of 3,837 Whitehall II cohort participants who were screened in 2008 to 2009, and followed for 11.7 years, without history of stroke, myocardial infarction, or coronary heart disease, were analyzed.

  • A high risk (hazard ratio, 2.99) was observed in participants in the highest aortic pulse wave velocity quartile; they reached the threshold for statin medication (7.5% risk) after 5 years whereas others reached it after 10 years.

  • As a result of adding aortic pulse wave velocity to the risk score, C statistic (0.68 vs 0.67) and net reclassification index (4.6% and 11.3%) improved.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
M3 app logo
Choose easy access to M3 India from your mobile!

M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen