Zekiy AO, et al. - In this investigation, experts studied the impact of nanostructured coating and antiseptic sealant on the outcomes of dental implantation. Clinically, 96 individuals were supervised. Study participants were assessed longitudinally during treatment and rehabilitation phases with clinical examinations, radiography, periodontal pathogen detection, and patient experience surveys. Relatively better hygienic indices were noted for patients receiving a nanocoated implant and an antiseptic sealant. Less contamination with periodontal pathogens occurred, bone density remained at the required level and overall treatment outcomes improved. Using a matrix to seal the dental implant-abutment interface with a nanostructured surface offers accurate results with respect to stable osseointegration and clinical and patient-reported therapy success outcomes.