Lee YF - An exploration was carried out of the prognosis of patients with Pisa syndrome following antipsychotic treatment for a 2-year period. Findings unveiled that Pisa syndrome was an uncommon adverse event that could also be chronic or recurrent, particularly among individuals with tardive onset. Experts cautioned regarding the risks in patients with the following predisposing factors: Old age, chronic psychosis, long-term antipsychotic use, advanced drug-induced Parkinsonism and combined pharmacologic treatment.

Methods

• Using a prospectively collected database, researchers selected 13 inpatients with Pisa syndrome following antipsychotic treatment between January 2012 to December 2014.
• Candidates were analyzed for a 2-year period.

Results

• Findings disclosed that the prevalence rate of Pisa syndrome during neuroleptic treatment was 0.45% in men and 0.37% in women, displaying a collective prevalence rate of 0.42%.
• It was determined that the mean age of patients with Pisa syndrome was 47 years.
• Herein a total of 8 (61.5%) subjects had a position with a tilt toward the right side.
• A tilt toward the left side was discovered in 5 (38.5%) individuals.
• As per the outcomes, the average Cobb angle of the trunk was 17.3 (SD, 4.0) degrees.
• Data demonstrated a markedly shorter duration of pattern of trunk dystonia (P=.024) on presentation with Pisa syndrome within 3 months of medication modification compared with that observed in the tardive-onset group.