Kelly DL, et al. - Herein, a hypothesis was tested that higher peripheral antigliadin antibodies (AGA IgG) would be associated with higher peripheral inflammation as measured by TNF-α and IL-1β in people with schizophrenia. Higher level of peripheral inflammation was exhibited by people with schizophrenia having higher levels of AGA IgG. These subjects may define a subgroup with distinct pathophysiology and potentially novel treatment targets.