Androgen receptor variants mediate DNA repair after prostate cancer irradiation
Cancer Research Sep 19, 2017
Yin Y, et al. - In order to figure out if androgen receptor variants mediate DNA repair after prostate cancer irradiation, experts conducted this study. For therapeutic targeting of DNA-PK in the context of combined androgen deprivation therapy (ADT) and radiotherapy as a strategy to radiosensitize clinically localized prostate cancer, a mechanistic rationale was provided.
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