Munuera-Gifre E, Saez M, Juvinyà-Canals D, et al. - In this cross-sectional study, researchers characterized the distribution of Type 2 DM retinal lesions and ascertained if it is symmetrical between the two eyes, is random or follows a certain pattern. The sample consisted of Type 2 DM patients who had been referred for an outpatients’ ophthalmology visit for diabetic retinopathy screening in primary health care. Using central projection non-mydriatic retinography, retinal photographic images were taken. Four thousand seven hundred seventy lesions were identified from among the 94 patients included in the study. DR lesion distribution is not homogeneous or random but follows a determined pattern for both microaneurysms/haemorrhages and hard exudates. This distribution means it is possible to identify the most vulnerable areas of the retina to metabolic alteration. The outcomes may be useful in automated DR detection algorithms and in determining the underlying physiopathological vascular and non-vascular mechanisms that may explain these differences.