Özen B, Sancakli O, Şenol HD, et al. - In the majority of pediatric cases of chronic urticaria (CU), it is not possible to determine the underlying cause/disease. In some cases, treatable triggers exist, as revealed in this study. Hence, each patient should be assessed with selected laboratory tests after detailed history and physical examination.

• In this study of 141 patients aged 0-18 years who were diagnosed with CU, the clinical and laboratory findings and demographic characteristics were examined and factors affecting prognosis were investigated.

• In participants, female/male ratio was 69/55, and median age at first visit was 9.5 years (min:1, max:17), an accompanying atopic disease was present in 44.5% and a chronic disease in 16.3%.

• Among participants, chronic spontaneous urticaria and chronic inducible urticaria (CIU) were detected in 88% and 12%, respectively.

• Of CIU cases, symptomatic dermographism, cholinergic urticaria, and cold urticaria was present in 72.2%, 16.7%, and 11.1%, respectively.

• In patients, intestinal parasitosis (n=14), anemia (n=10) and urinary tract infection (n=8) were documented as most common pathological findings.

• Median total disease span was 47 weeks (min:8, max:284), and a longer span was evident in patients with atopy.

• The highest eosinophil count was detected in the group that went into remission with standard-dose antihistamine.