Meng L, Wang Z, Reilly M, et al. - Researchers sought the risk factors that can aid in recognition of the possibility of pregnancy loss in threatened late miscarriage (TLM) patients with and without spontaneous uterine contractions. They assayed amniotic immune biomarkers (IL2β receptor, IL6, IL8, IL10, IL1β, and TNFα) and assessed “sludge”. Treatment was provided to patients without intrauterine infections and followed‐up until delivery, and pregnancy outcomes were recorded. The group with contractions had higher amniotic levels of IL2βR, IL8, and TNFα. Among TLM patients without intrauterine infections, there were differences in amniotic immune biomarkers between patients with different symptoms; these differed not only for their levels but also for the impact of these biomarkers on the risk of late miscarriage. Findings thereby emphasize considering the symptoms of TLM in the study of miscarriage risk.