Zhang J, et al. - In this meta-analysis, authors assessed the role of combination therapy (α-blockers and PDE5-Is) in patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia (LUTS/BPH). A significant improvement in the international prostate symptom score, maximum urinary flow rate, and international index of erectile function in patients with LUTS/BPH could be achieved with the combination therapy. Findings suggested a greater suitability of combination therapy for these patients.