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Alcohol use disorder and non‐fatal suicide attempt: Findings from a Swedish National Cohort Study

Addiction Jun 27, 2021

Edwards AC, Ohlsson H, Mościcki E, et al. - This study attempted to assess the strength and mechanistic nature of the association between alcohol use disorder (AUD) and increased suicide attempt and determine any causal pathways and/or shared risk factors. Cox proportional hazards models in population-level and co-relative analyses were used to calculate the risk of first non-fatal suicide attempt as a function of previous AUD. Researchers used continuously updated longitudinal nationwide Swedish registry data on native Swedes born 1950-1970 (N=2,229,619) and followed from age 15 until 2012. Alcohol use disorder seems to be an important predictor of suicide attempt even in the context of other psychiatric disorders in Sweden. The results reveal that observed relationship is likely the outcome of features that jointly impact risk of AUD and suicide attempts (genetic liability, psychiatric illness, childhood stressors) and a potentially causal pathway, acting independently or in conjunction with one another.

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