Yong SB, et al. – Via analysis of data obtained from over 100,000 children in the National Taiwan Health insurance Database, researchers clarified the development of juvenile idiopathic arthritis (JIA) to adult-onset autoimmune diseases in this population-based study. Both patients with (n=262) and without (n=107,171) JIA were followed up until December 2013 to investigate their adult-onset autoimmune disease outcomes after reaching the age of 16. Investigators found that patients with JIA history had an incidence rate of 83.56 per 10⁵ person-months for rheumatoid arthritis (RA), 16.61 for systemic lupus erythematosus (SLE), 58.39 for ankylosing spondylitis (AS), and 33.26 for psoriatic diseases. Ultimately, in adulthood, children with JIA had an increased risk of developing RA, AS, psoriatic disease, and SLE.