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Adrenal insufficiency in children with eosinophilic esophagitis treated with topical corticosteroids

Journal of Pediatric Gastroenterology and Nutrition Mar 04, 2020

Bose P, Kumar S, Nebesio TD, et al. - In this multipart study, researchers identified practices of gastroenterologists screening for adrenal insufficiency (AI) and reported prevalence of AI in children with eosinophilic esophagitis (EoE) treated with topical corticosteroids (TCS), as well as contrasted serum dehydroepiandrosterone sulfate (DHEA-S) levels to morning serum cortisol (MSC) levels as screening tool for AI. According to findings, EoE consortia gastroenterologists were more likely to screen for AI. Data reported that AI prevalence in the prospective cohort was 5%. DHEA-S has a moderate association with MSC levels, but there is a need for more data to determine usefulness as an AI screening tool.
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