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Admission lactate and base deficit in predicting outcomes of pediatric trauma

Shock Mar 31, 2021

Huh Y, Hwang K, Jung K, et al. - Researchers aimed at comparing the predictive value of admission lactate and base deficit (BD), which physiologically indicate early hemorrhagic shock, for outcomes following pediatric trauma. They assessed data of 545 children with trauma who visited a Korean academic hospital from 2010 through 2018. Mortality, transfusion, and surgical interventions were reported in 7.0%, 43.5%, and 14.9%, respectively. For each outcome, the following cutoffs of lactate and BD were identified: mortality, 5.1 and 6.7 mmol/L; transfusion, 3.2 and 4.9 mmol/L; and surgical interventions, 2.9 and 5.2 mmol/L, respectively. Overall, findings suggest more strong association of lactate with mortality. In contrast, there appeared a marginally stronger association of BD with the need for hemorrhage-related procedures.

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