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Adherence to beta‐blockers and long‐term risk of heart failure and mortality after a myocardial infarction

ESC Heart Failure Dec 16, 2020

Desta L, Khedri M, Jernberg T, et al. - Researchers assessed long‐term risk of heart failure (HF) and death in correlation with adherence to beta‐blocker therapy following a first acute myocardial infarction (AMI). After applying inclusion and exclusion criteria, there were 38,608 patients in the final analysis. During the subsequent 4 years of follow up, adherence was found to be independently related to lower all‐cause death and a lower risk for the composite of HF readmission/death. Non-adherence to beta‐blockers within the first year was found in nearly one in three AMI patients. Findings revealed an independent link of adherence with improved long‐term results; however, there remained uncertainty for patients with HFNEF [HF and normal ejection fraction (EF)] and normal EF. Better adherence was reported in relation to factors including being married/cohabiting and having higher income level, hypertension, ST‐elevation myocardial infarction, and percutaneous coronary intervention.

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