Blanca-Lopez N, et al. - This study was designed to phenotype a group of children with hypersensitivity reactions to nonsteroidal anti-inflammatory drugs (NSAIDs), including paracetamol. Researchers also analyzed the degree of agreement with the entities reported in adults and how they fit the proposed classifications. Findings reported that 83% of the total number of cases confirmed with NSAID hypersensitivity were cross-intolerant. Furthermore, it was observed that both cutaneous and respiratory manifestations were common in cross-intolerant reactions. It was evident that acetyl salicylic acid challenge, as the first approach, was safe as well as useful to establish the diagnosis.