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Accuracy of diagnostic tests for Schistosoma mansoni infection in asymptomatic Eritrean refugees: Serology and point-of-care circulating cathodic antigen against stool microscopy

Clinical Infectious Diseases Aug 11, 2017

Chernet A, et al. – In this study, the accuracy of 3 different diagnostic tests for S. mansoni infection (stool microscopy [samples prepared by sedimentation technique], serology, and point–of–care circulating cathodic antigen [POC–CCA] urine cassette test) was assessed in newly arrived asymptomatic Eritrean refugees in Switzerland. For asymptomatic S. mansoni infection, the combination of serology plus urine POC–CCA testing indicated a sensitivity of 100% (95% confidence interval, 82.2%–100%), this suggested it as the most sensitive screening option in Eritrean refugees, compared with stool sedimentation microscopy.
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