Molina I, et al. – The main purpose of the present study was to assess the fatigue resistance and failure mode of novel–design implant restorations made of histoanatomic computer–assisted design/computer–assisted manufacturing (CAD/CAM) bilaminar bonded assemblies. The present data indicated that lithium disilicate monolithic restorations and mesostructures with nanofilled composite resin veneer showed higher survival rates when compared with nanofilled composite resin restorations.