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Absolute basophil count is associated with time to recurrence in patients with high-grade T1 bladder cancer receiving Bacillus Calmette–Guerin after transurethral resection of the bladder tumor

World Journal of Urology Apr 22, 2019

Ferro M, et al. - Researchers in this study investigated 1,045 candidates to analyze if baseline counts of basophils, eosinophils, and monocytes have any predictive value for the outcomes of high-grade T1 bladder cancer cases receiving a standard course of intravesical BCG. During follow-up, they recorded 678 recurrences, 303 progressions, and 150 deaths. They found an association of logarithmic transformation of basophils count with a 30% increase in the hazard of recurrence per unit increase of logarithmic basophils count. They reported that the basophil count modeled by quartiles was also significantly correlated with time to recurrence. They suggested that the recurrence in BCG-treated HG/G3 T1 bladder cancer cases might be predicted with baseline basophil count.

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