Florio AA, Campbell PT, Zhang X, et al. - Researchers evaluated the link between waist and hip circumference and the risk of primary liver cancer (PLC) overall and by histologic type – hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) in a consortium of prospective cohort investigations, named the Liver Cancer Pooling Project, that incorporates data from 1,167,244 people (PLC n = 2,208, HCC n = 1,154, ICC n = 335). An increased risk of liver cancer was observed in relation to excess abdominal size, this was seen even in people considered to have a normal BMI. However, no increased risk was evident in relation to excess gluteofemoral size alone. Previous analyses revealing a link between excess adiposity and risk of liver cancer were extended by these findings by untangling the separate influences of excess abdominal and gluteofemoral size by using both waist and hip circumference measurements.