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Abbreviated MRI for hepatocellular carcinoma screening: A systematic review and meta-analysis

Journal of Hepatology Feb 07, 2021

Gupta P, Soundararajan R, Patel A, et al. - A systematic review was performed to ascertain the diagnostic accuracy of abbreviated MRI (AMRI) in hepatocellular carcinoma (HCC) screening. Researchers carried out a search in the MEDLINE and EMBASE databases for studies assessing the diagnostic accuracy of AMRI in the screening of HCC. They compared the diagnostic performance of AMRI with the ultrasound. The QUADAS-2 tool was applied to evaluate the quality of studies. Of the 11,327 studies screened by titles, the final analysis included 15 studies (3 prospective and 12 retrospective, 2,807 patients, 917 with HCC). For HCC screening, AMRI has high sensitivity and specificity. The results indicate that different AMRI protocols have similar diagnostic performance. The pooled per-patient sensitivity and specificity were 86% and 94%, respectively. Ultrasound had a lower sensitivity than AMRI.

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