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A worldwide perspective of sepsis epidemiology and survival according to age: Observational data from the ICON audit

Journal of Critical Care Feb 20, 2019

Kotfis K, et al. - In this secondary analysis of data from the prospective ICON audit, researchers assessed age-related disparities in the outcomes of critically ill patients with sepsis around the world. Participants included all adult (>16 years) patients who sought ICU admission between May 8 and 18, 2012. Only admissions for routine postoperative observation were not included. Overall, 10,012 patients had completed age data, these subjects were included and were grouped as – <50, 51–60, 61–70, 71–80, >80 years. Infection plus at least one organ failure was accepted as the definition of sepsis. Sepsis was detected in 2963 patients. Similar proportions were seen across the age groups (<50 = 25.2%; 51–60 = 30.3%; 61–70 = 32.8%; 71–80 = 30.7%; >81 = 30.9%). With age, an increase in the odds for death was noted. Between the ages of 71 and 77 years, the maximal rate of increase was documented.
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