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A retrospective analysis of distinguishing features of chest HRCT and clinical manifestation in primary Sjögren’s syndrome-related interstitial lung disease in a Chinese population

Clinical Rheumatology Oct 26, 2018

Dong X, et al. - Researchers described the distinctive chest high-resolution computerized tomography (HRCT) features and clinical manifestations of primary Sjögren syndrome (pSS)-related interstitial lung disease (ILD). They retrospectively analyzed the demographic data, clinical manifestations, and laboratory and radiological findings of 527 pSS patients. Reticular pattern (92.7%), ground-glass attenuation (87.4%), and bronchovascular bundle thickening (82%) are the most commonly seen abnormalities in HRCT. The most frequently seen patterns are the single pattern of non-specific interstitial pneumonitis (NSIP) and usual interstitial pneumonia (UIP) in HRCT, and multiple patterns in HRCT are seen in about 40% of the pSS-ILD patients. The pulmonary imaging features of pSS-ILD cannot be completely included in the classification of idiopathic pulmonary fibrosis.

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