Uçkay I, et al. - In this single-center, investigator-blinded pilot study, researchers investigated if adding a topical therapy with gentamicin-sponges to systemic antibiotic therapy could improve the healing of infected diabetic foot ulcers (DFUI). Patients with DFUI were randomized (1:1) to the gentamicin-sponge with systemic antibiotic vs systemic antibiotics alone. The gentamicin-sponge arm seemed to display a more rapid healing. However, the multivariate analysis, adjusting for the case-mix, suggested no significant association of the variable “gentamicin-sponge” with “cure and improvement.” With no ascribed adverse events, gentamicin-sponges were very well tolerated, however overall cure was not improved.