Boustedt K, et al. - In a cohort of preschool children, researchers explored the connection between early childhood caries and perinatal and metabolic risk factors. The study population comprised of 208 children who followed 6.5 years from birth. Indicators of the metabolic syndrome (waist circumference, blood pressure, fasting insulin, glucose, and dyslipidaemia) have been recorded at 6.5 years of age. According to results, infants born moderately to late preterm and infants born small for gestational age were more likely to have caries of early childhood at age five. Born preterm or small for gestational age has increased the risk of caries from early childhood. Preschool children with caries showed higher levels of fasting glucose but no other signs of metabolic syndrome.