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A promising new predictive factor for detecting bowel resection in childhood intussusception: The lymphocyte-C-reactive protein ratio

BMC Pediatrics Dec 22, 2021

Chen B, Cao J, Yan C, et al. - Findings demonstrate the usefulness of preoperative LCR level (lymphocyte–CRP ratio) as a marker to foretell the requirement for intestinal resection due to intestinal necrosis in intussusception cases.

  • This cohort included 115 pediatric patients who underwent operations for intussusception; of these, 47 (40.9%) underwent intestinal resections.

  • Significantly higher values for neutrophil count, CRP level, platelet–lymphocyte ratio, neutrophil–lymphocyte ratio, and LCR (lymphocyte–CRP ratio) were found in patients with intestinal resection vs those without any resection.

  • By receiver operating characteristic analysis, combination of lymphocytic count along with C-reactive protein levels (LCR) showed the highest correlation with intestinal resection due to intussusception vs other parameters in the patients, with sensitivity and specificity of 0.82 and 0.80, respectively, for the diagnosis of strangulation.

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