Mejia SB, et al. - Because the FDA is considering revoking the heart-health claim for soy protein due to a perceived lack of consistent reduction in low-density lipoprotein cholesterol (LDL-C) levels in randomized, controlled trials, researchers conducted a meta-analysis that included adult men and women from 46 trials that the FDA will use to make its decision regarding revocation of the heart-health claim for soy protein. Participants had baseline circulating LDL-C levels ranging from 110 to 201 mg/dL. According to findings, in adults, soy protein significantly reduced LDL-C levels by about 3% to 4%. These data, thus, supported the international advice given to the general public to increase the intake of plant protein.