A low-carbohydrate protein-rich bedtime snack to control fasting and nocturnal glucose in type 2 diabetes: a randomized trial
Clinical Nutrition Mar 23, 2020
Abbie E, et al. - This study was undertaken to ascertain whether a low-carbohydrate protein-rich bedtime snack (Egg) could reduce fasting plasma glucose levels in people with type 2 diabetes when compared with a high-carbohydrate protein-rich bedtime snack (Yogurt) or a No Bedtime Snack condition. Glucose control measured by continuous glucose monitoring (CGM) and fasting insulin sensitivity markers were considered as secondary outcomes. Applying a randomized crossover design, individuals with type 2 diabetes (N = 15) completed three separate isocaloric conditions: Egg, Yogurt, and No Bedtime Snack, each lasting three days. Researchers obtained CGM throughout and duplicate fasting blood samples were collected on the morning of day 4 in each condition. Compared with a high-carbohydrate protein-matched bedtime snack (Yogurt), it was reported that a low-carbohydrate bedtime snack (Egg) lowered fasting glucose and improved markers of insulin sensitivity. Nevertheless, the study found that consuming a low- or high-carbohydrate bedtime snack did not seem to reduce fasting glucose compared to consuming an isocaloric diet with no bedtime snack.
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