Jacobsen BK, et al. - In this study, researchers delineated the age- and gender-specific longitudinal changes in weight and waist circumference in a rural Norwegian population with a high proportion of the indigenous Sami population. Two population-based surveys, SAMINOR 1 (2003–2004) and SAMINOR 2 (2012–2014), were assessed for longitudinal shifts in weight and waist circumference according to age at baseline in the SAMINOR 1 Survey and gender during the 10-year period. They performed analysis of 1,538 men and 1,958 women [aged 36 to 69 at baseline (the birth year 1934 to 1967); 41% Sami]. In men and women, mean weight increase of 0.8 kg (95% confidence interval: 0.5, 1.1) and 0.3 kg (95% confidence interval: 0, 0.5) was reported. During the 10-year follow-up, younger individuals gained significantly more weight than older participants in both men and women. Men aged 36–54 and women aged 36–49 at baseline exhibited a statistically significant increase in the mean weight; this was statistically significantly reduced in men and women aged 60–69. The mean waist circumference increased by 6.3 cm (95% confidence interval: 6.0, 6.6) and 8.4 cm (95% confidence interval 8.1, 8.8) in men and women, respectively. All age groups exhibited a statistically significant increase in the mean waist circumference from SAMINOR 1 to SAMINOR 2, and there was an inverse correlation between age at baseline and change in waist circumference. Both Sami and non-Sami participants showed the inverse correlations between age at baseline in SAMINOR 1 and the 10-year change in weight and waist circumference. In view of these findings, they emphasize the necessity for the prevention of obesity, particularly in younger people, as it is difficult to achieve permanent weight loss.