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A comparison between point-of-care testing and venous glucose determination for the diagnosis of diabetes mellitus 6–12 weeks after gestational diabetes

Diabetic Medicine Jan 24, 2019

Coetzee A, et al. - In 122 South African women with gestational diabetes (GDM), researchers assessed point-of-care-testing (POCT) for the diagnosis of type 2 diabetes mellitus 6–12 weeks post-partum. Individuals with known pre-existing diabetes were excluded from the study. Bland–Altman plots and paired analysis were used to evaluate the analytical accuracy of POCT, while its diagnostic performance was determined using positive and negative predictive values for the calculation of specificity and sensitivity. In 78% of women with a positive predictive value of 89.3% and a negative predictive value of 96.7% at fasting time, POCT correctly identified type 2 diabetes. They found that the sensitivity and specificity of POCT to the diagnosis of type 2 diabetes were 89% (fasting), 85.7% (2 hours), and 96.7% (fasting), 98.5% (2 hours), respectively. They noted that POCT was less sensitive to pre-diabetes diagnosis (69%) but showed satisfactory specificity (92%) at both time points. Overall, the investigators concluded that POCT identifies women with type 2 diabetes 6 to 12 weeks after GDM with accuracy.

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