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A 2018 Italian and Romanian survey on subclinical hypothyroidism in pregnancy

European Thyroid Journal Aug 02, 2018

Negro R, et al. - Among Italian and Romanian endocrinologists, researchers studied the management of subclinical hypothyroidism and chronic autoimmune thyroiditis in pregnancy. They found that respondents globally seemed knowledgeable about managing thyroid autoimmunity and subclinical hypothyroidism during pregnancy, though researchers preferred a more aggressive implementation of iodine supplementation. Most surveyed endocrinologists believed there was a relationship between mild thyroid impairment and adverse outcomes in pregnancy.

Methods

  • For this analysis, members of the Associazione Medici Endocrinologi and Romanian Society of Endocrinology were asked to take part in a web-based survey investigating the topic.

Results

  • Nine hundred two people took an interest in the survey, 759 of whom completed all sections.
  • The present data indicated that 85.1% were aware of the 2017 American Thyroid Association guidelines about thyroid disease and pregnancy, and 82.9% declared that TSH screening at the beginning of pregnancy is warranted.
  • It was observed that 53.6% considered 2.5 mIU/L and 26.2% considered 4.0 mIU/L as the upper normal limit of TSH, and 50% would treat a patient with TSH 3.5 mIU/L with levothyroxine in a patient negative for peroxidase antibodies.
  • Findings revealed that approximately 20% did not recommend iodine supplementation.
  • In the first trimester, isolated hypothyroxinemia detected would be treated by 40.8%.
  • A TSH < 2.5 mIU/L would be targeted by 70% in patients undergoing ovarian stimulation.
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