Schubert SA, et al. - Researchers investigated how preoperative beta-blocker administration prior to aortic valve replacement (AVR) impacts patient outcomes. Using a multi-institutional, statewide database comprised of Society of Thoracic Surgeons data, they extracted data from 7,380 patients who underwent isolated AVR from 2002 to 2016; of these, 53% received a preoperative beta-blocker. Findings revealed no improved outcomes after AVR but rather increased postoperative morbidity in correlation with preoperative beta-blocker administration. Hence, this study did not support routine initiation of preoperative beta-blockade in patients undergoing AVR.