Ng SP, et al. - In 1,508 patients who were treated definitively with radiotherapy for head and neck cancer (HNC) from 2000 through 2010, the effectiveness of surveillance imaging was investigated. This study included patients with a demonstrable disease-free interval (≥1 follow-up imaging procedure without evidence of disease and a subsequent visit/imaging procedure). Imaging allowed earlier detection of disease recurrence, but chances of receiving salvage therapy were significantly higher among those patients in the group of patients with clinically detected disease recurrence vs those whose recurrence was detected on imaging. Between clinically-detected patients with disease recurrences and those detected by imaging alone, overall survival did not differ. Low yield and a high cost of surveillance imaging were observed in asymptomatic patients with HNC who were treated definitively with radiotherapy and had no clinically suspicious findings beyond 2 years.