Schell J, et al. - In obese adults with type 2 diabetes, researchers studied the effects of daily dietary raspberries on postprandial and 4-week fasting glucose, lipids, and biomarkers of inflammation. This investigation was a randomized crossover study with two different phases: a postprandial phase of acute raspberry supplementation (2 separate days at least 1 week apart), followed by a 1-week washout phase, and then a 10-week diet supplement phase—with and without raspberry supplementation periods of 4 weeks each—separated by 2-week washout phase. After the raspberry vs control phase, the postprandial phase showed significantly lower levels of serum glucose at 2 and 4 hours postprandial. Furthermore, interleukin (IL)-6 and high-sensitivity tumor necrosis factor alpha (hsTNF-α) were lower in serum biomarkers of inflammation at 4 hours postprandial following raspberry vs control meal. In the raspberry vs control phase, postprandial serum triglycerides showed a declining trend at 4 hours. In adults with diabetes, dietary raspberries, which are low in calories and high in polyphenols and other nutrients, might reduce postprandial hyperglycemia and inflammation and generally have selected anti-inflammatory effects. There were no effects on fasting glucose and lipids, C-reactive protein, and arterial elasticity.