Jung SY, et al. - In this study involving 146,377 Korean female cancer survivors, researchers investigated whether BMI before the diagnosis of the first primary cancer has any impact on the development of secondary primary cancers (SPCs). After 565,877 person-years of follow-up, SPC developed in 2,222 patients. Findings revealed positive linear trends between pre-diagnosis BMI and the risk of overall, colorectal, ovary, thyroid, and obesity-related SPCs. This suggested that pre-diagnosis obesity may be a risk factor for overall, individual, and obesity-related SPCs in female cancer survivors. However, the BMI-SPC risk association was of similar magnitude to that observed for first cancers in the general population.