Rentsch CT, et al. - Given the independent contribution of HIV, hepatitis C virus (HCV), and alcohol-related diagnoses (ARD) to increased risk of all-cause hospitalization, researchers determined annual medical intensive care unit (MICU) admission rates and relative risk of MICU admission between 1997 and 2014 among people with and without HIV, HCV, and ARD, using data from the largest HIV and HCV care provider in the United States. They calculated annual MICU admission rates among 155,550 patients in the Veterans Aging Cohort Study by HIV, HCV, and ARD status, identifying HCV infection and ARD as the key contributors to MICU admission risk. Combination of treatment of HIV, HCV, and interventions targeting unhealthy alcohol use may reduce the impact of each of these conditions.