Shantsila E, et al. - Researchers investigated the links between monocyte subsets, their phagocytic and nuclear factor κB (NFκB) activity, and outcomes in ST-elevation myocardial infarction (STEMI). Using flow cytometry, they determined monocyte subsets and their phagocytic activity and intracellular levels of inhibitory κB kinase β (IKKβ, marker of NFκB activity) in 245 patients with STEMI, with median follow-up of 46 months. Findings revealed the independent predictive value of Mon2 (CD14++CD16+CCR2+) counts for major adverse cardiovascular events. The relation of Mon2 with the occurrence of HF was strongly and independently related to functional status, suggestion potential therapeutic implications.