Gariani K, et al. – In his study, researchers determined the most appropriate duration of antibiotic treatment for diabetic foot infections (DFIs). Specifically, they developed a cluster-controlled Cox regression model using a clinical pathway for adult patients with DFI to evaluate factors related to infection remission, accentuating antibiotic-related parameters. Total amputations due to DFI and DFI episodes with a follow-up time of < 2 months were excluded. Among 1,018 DFI episodes in 482 patients, 392 had osteomyelitis, 626 soft tissue infections, 246 large abscesses, 322 cellulitis, and 335 necrosis. The investigators noted that 313 cases involved revascularization. Overall, no conclusive optimal duration or route of administration of antibiotic therapy was found to prevent DFI recurrences. These limited data could potentially support a shorter treatment duration for patients with DFI.