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Exploration of the role of anti-Mullerian hormone and LH/FSH ratio in diagnosis of polycystic ovary syndrome

Clinical Endocrinology Jan 17, 2019

Le MT, et al. - In this multicenter cross-sectional descriptive study, researchers explored the role of anti-Mullerian hormone (AMH) and LH/FSH ratio in diagnosis of polycystic ovary syndrome (PCOS). A total of 863 infertile women aged 18-45 were assessed at 3 infertility centres in Vietnam and recruited from June 2016 to June 2017. According to findings, serum AMH concentration value was found to be not significantly higher than the LH/FSH ratio in PCOS diagnosis. Although these biomarkers are not suitable separately for the diagnosis of PCOS based on their own value, the combination of different endocrine factors, including AMH, LH and LH/FSH ratios, together with BMI and other anthropometric and clinical characteristics can offer additional value for the diagnosis of PCOS.
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